196889

Springer, Dordrecht

2015

316 Pages

ISBN 978-3-319-17105-0

Contextualizing systems biology

presuppositions and implications of a new approach in biology

Martin Dring, Martin Döring, Imme Petersen, Anne Brüninghaus, Regine Kollek

This collective monograph aims at contributing to an improved understanding of the epistemic presumptions, sociocultural implications and historically backgrounds of the newly emerging and currently expanding approach of systems biology. In doing so, it offers empirically grounded, valuable and reflexive information about a paradigmatic shift in the biosciences for a wide range of scientists working in the interdisciplinary areas of systems biology, synthetic biology, molecular biology, biology, the philosophy of science, the sociology of science and scientific knowledge, science andtechnology studies, technology assessment and the like. The authors of this monograph share the theoretical methodological premise that science is a culturally and socially embedded practice which characterizes our culture as a scientific one and at the same time draws its innovative potential from its sociocultural context. This dialectic relationship lies at the heart of the current development of systems biology which is conceived as a so-called successor of "-omics' research and triggered by high-throughput information technologies. At the same time a need for a holistic conceptualization of complex biological processes emerges.

As the title Contextualizing Systems Biology suggests, this book analyzes the development and advent of systems biology from different theoretical and methodological perspectives. In empirically analyzing these different and interrelated layers and dimensions of systems biology, the scope of the book goes beyond present attempts to investigate the advent of new approaches in the biological sciences as it frames and assesses systems biology from an interdisciplinary and integrated perspective.

 

Publication details

Full citation:

Dring, M. , Döring, M. , Petersen, I. , Brüninghaus, A. , Kollek, R. (2015). Contextualizing systems biology: presuppositions and implications of a new approach in biology, Springer, Dordrecht.

Table of Contents

Understanding systems biology

Kollek Regine; Petersen Imme; Brüninghaus Anne; Döring Martin

1-26

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Basic concepts of systems biology as seen through systems biologists' eyes

Döring Martin; Kollek Regine; Brüninghaus Anne; Petersen Imme

27-118

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Systems-oriented approaches in biology

Döring Martin; Kollek Regine; Petersen Imme; Brüninghaus Anne

119-146

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Systems biology, information technology, and cancer research

Petersen Imme; Kollek Regine; Döring Martin; Brüninghaus Anne

147-211

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Science policy of systems biology

Brüninghaus Anne; Petersen Imme; Kollek Regine; Döring Martin

213-260

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Systems biology goes public

Brüninghaus Anne; Döring Martin; Kollek Regine; Petersen Imme

261-281

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Back into future

Kollek Regine; Petersen Imme; Döring Martin; Brüninghaus Anne

283-301

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